Free CCMA practice · Updated October 2026

CCMA anatomy and physiology practice questions, with every answer explained

Anatomy and physiology is 8 of the 150 scored items on the NHA CCMA. Answer 10 exam style questions on anatomy and physiology and see exactly which concepts would cost you points on test day.

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Where the CCMA points are150 scored items
General patient care
28
Foundational knowledge
15
Infection control and safety
15
Patient intake and vitals
14
Phlebotomy
12
Care coordination and education
12
Administrative assisting
12
Anatomy and physiology
8
Source: NHA CCMA test plan (2022)You are here ↑
Score 0/0
Q1Body organization

What is the basic structural and functional unit of all living things?

What these anatomy and physiology questions test

These questions cover body organization, integumentary, musculoskeletal, nervous system and special senses. Each one shows the correct answer and why every other option is wrong, so a miss tells you exactly what to review before the CCMA.

Body organizationIntegumentaryMusculoskeletalNervous systemSpecial sensesCardiovascularLymphatic and immuneBlood

All 10 questions with answers explained

Prefer to read first? Every question from the practice set above, with the correct answer and why each wrong option is wrong.

Q1What is the basic structural and functional unit of all living things?
  1. The cell
  2. The organ system
  3. The organ
  4. The tissue

Answer: A. The cell is the smallest unit of life. Cells form tissues, tissues form organs, and organs work together in organ systems.

Why not B: Organ systems are groups of organs.

Why not C: Organs are made of different tissues.

Why not D: Tissues are groups of similar cells.

Exam tactic: Cell → tissue → organ → system → organism.

Q2Which is the outermost layer of the skin?
  1. Epidermis
  2. Subcutaneous layer
  3. Dermis
  4. Muscle layer

Answer: A. The epidermis is the outer, avascular layer. The dermis beneath contains blood vessels, nerves, and glands, and the subcutaneous layer contains fat.

Why not B: The subcutaneous layer is below the dermis.

Why not C: The dermis lies beneath the epidermis.

Why not D: Muscle is not a layer of the skin.

Exam tactic: Epi = upon. Epidermis on top.

Q3Which connective tissue structure attaches a muscle to a bone?
  1. Cartilage
  2. Tendons
  3. Bursae
  4. Ligaments

Answer: B. Tendons attach muscles to bones. Ligaments connect bone to bone, cartilage cushions joints, and bursae are fluid-filled sacs that reduce friction.

Why not A: Cartilage cushions and covers joint surfaces.

Why not C: Bursae reduce friction around joints.

Why not D: Ligaments connect bone to bone.

Exam tactic: Tendon: muscle to bone. Ligament: bone to bone.

Q4What makes up the central nervous system?
  1. The heart and blood vessels
  2. The cranial and spinal nerves
  3. The sensory organs only
  4. The brain and spinal cord

Answer: D. The central nervous system is the brain and spinal cord. The peripheral nervous system includes the cranial and spinal nerves that connect the CNS to the rest of the body.

Why not A: Heart and vessels are cardiovascular.

Why not B: Cranial and spinal nerves are peripheral.

Why not C: Sense organs connect through peripheral nerves.

Exam tactic: CNS = brain + cord.

Q5Where are the light-sensitive receptors (rods and cones) located in the eye?
  1. Cornea
  2. Lens
  3. Iris
  4. Retina

Answer: D. The retina lines the back of the eye and contains rods (dim light) and cones (color and detail), which send signals through the optic nerve.

Why not A: The cornea is the clear front surface that bends light.

Why not B: The lens focuses light onto the retina.

Why not C: The iris is the colored part that controls pupil size.

Exam tactic: Retina = the eye's film.

Q6Which valve separates the left atrium from the left ventricle?
  1. Mitral (bicuspid) valve
  2. Tricuspid (right AV) valve
  3. Pulmonary semilunar valve
  4. Aortic semilunar valve

Answer: A. The mitral valve is between the left atrium and left ventricle. The tricuspid valve is between the right atrium and right ventricle; the pulmonary and aortic valves guard the outflow tracts.

Why not B: The tricuspid valve is on the right side.

Why not C: The pulmonary valve opens to the pulmonary artery.

Why not D: The aortic valve opens to the aorta.

Exam tactic: Tri on the right, mitral (bi) on the left.

Q7What is the main function of the lymphatic system?
  1. Return tissue fluid to the blood and help fight infection
  2. Pump blood through the arteries to the tissues
  3. Filter wastes from the blood and form urine
  4. Produce the digestive enzymes that break down food

Answer: A. The lymphatic system collects excess tissue fluid (lymph) and returns it to the bloodstream, and its lymph nodes filter pathogens and house immune cells. It also absorbs dietary fats.

Why not B: The heart pumps blood.

Why not C: The kidneys filter blood to form urine.

Why not D: Digestive enzymes come from the pancreas and gut.

Exam tactic: Lymph: drainage + defense.

Q8Why is a person with type O negative blood called a universal donor?
  1. Their red cells lack A, B, and Rh antigens
  2. They can receive any blood type
  3. Their plasma contains no antibodies
  4. Their blood clots faster than other types

Answer: A. Type O negative red cells have no A, B, or Rh(D) antigens, so they are unlikely to be attacked by a recipient's antibodies in an emergency. AB positive individuals are considered universal recipients.

Why not B: The universal recipient is AB positive.

Why not C: Type O plasma actually contains both anti-A and anti-B antibodies.

Why not D: Blood type does not determine clotting speed.

Exam tactic: O neg gives to all. AB pos receives from all.

Q9Which body cavity contains the heart and lungs?
  1. Abdominal cavity
  2. Cranial cavity
  3. Thoracic cavity
  4. Pelvic cavity

Answer: C. The thoracic cavity, above the diaphragm, contains the heart (in the mediastinum) and lungs (in the pleural cavities).

Why not A: The abdominal cavity holds the stomach, intestines, liver, and other organs.

Why not B: The cranial cavity holds the brain.

Why not D: The pelvic cavity holds the bladder and reproductive organs.

Exam tactic: The diaphragm separates the thoracic and abdominal cavities.

Q10Which glands in the skin produce oil (sebum)?
  1. Sudoriferous glands
  2. Sebaceous glands
  3. Lacrimal glands
  4. Mammary glands

Answer: B. Sebaceous glands, usually associated with hair follicles, secrete sebum that lubricates skin and hair. Sudoriferous glands produce sweat.

Why not A: Sudoriferous glands produce sweat.

Why not C: Lacrimal glands produce tears.

Why not D: Mammary glands produce milk.

Exam tactic: Sebaceous = sebum (oil). Sudoriferous = sweat.

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More about the CCMA

PassPulse is an independent exam preparation tool. We are not affiliated with, endorsed by, or sponsored by the National Healthcareer Association (NHA), the American Association of Medical Assistants (AAMA), American Medical Technologists (AMT) or the National Center for Competency Testing (NCCT). Exam, credential and product names mentioned on this page are trademarks of their respective owners and are used only to identify the exams described.

These practice questions are written by PassPulse to reflect the published exam content outline. They are not actual exam questions. Questions, answers and explanations may contain errors or be out of date, and they are for exam study only, not for clinical or professional practice: always check facts against the certifying body's official materials, current standards and your employer's policies. Scores and projections on this page are estimates based on a small number of questions and do not predict your result on the real exam. Area weights come from the official outline as of the date shown; always confirm current exam details with the certifying body.
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