Free CCMA practice · Updated October 2026

CCMA cardiovascular, immune and endocrine systems practice questions, with every answer explained

Anatomy and physiology is 8 of the 150 scored items on the NHA CCMA. Answer 10 exam style questions on cardiovascular, immune and endocrine systems and see exactly which concepts would cost you points on test day.

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Where the CCMA points are150 scored items
General patient care
28
Foundational knowledge
15
Infection control and safety
15
Patient intake and vitals
14
Phlebotomy
12
Care coordination and education
12
Administrative assisting
12
Anatomy and physiology
8
Source: NHA CCMA test plan (2022)You are here ↑
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Q1Cardiovascular

Which heart chamber pumps oxygenated blood out to the body?

What these cardiovascular, immune and endocrine systems questions test

These questions cover cardiovascular, blood, lymphatic and immune, endocrine and special senses. Each one shows the correct answer and why every other option is wrong, so a miss tells you exactly what to review before the CCMA.

CardiovascularBloodLymphatic and immuneEndocrineSpecial sensesMusculoskeletalIntegumentaryRespiratoryDigestiveNervous system

All 10 questions with answers explained

Prefer to read first? Every question from the practice set above, with the correct answer and why each wrong option is wrong.

Q1Which heart chamber pumps oxygenated blood out to the body?
  1. Right ventricle
  2. Left ventricle
  3. Right atrium
  4. Left atrium

Answer: B. The left ventricle pumps oxygen-rich blood into the aorta and out to the body. Its wall is the thickest of the four chambers because it works against the highest pressure.

Why not A: The right ventricle pumps blood to the lungs.

Why not C: The right atrium receives blood from the body.

Why not D: The left atrium receives blood from the lungs.

Exam tactic: Left ventricle → aorta → body.

Q2What makes up about 55% of whole blood volume?
  1. White blood cells
  2. Plasma
  3. Platelets
  4. Red blood cells

Answer: B. Plasma, the liquid portion of blood, makes up about 55% of blood volume; formed elements make up the rest, mostly red blood cells.

Why not A: White cells are a very small fraction.

Why not C: Platelets are a very small fraction.

Why not D: Red cells make up most of the remaining 45%.

Exam tactic: Plasma = the liquid majority.

Q3Which cells produce antibodies?
  1. Plasma cells
  2. Thrombocytes
  3. Erythrocytes
  4. Osteocytes

Answer: A. Plasma cells, which develop from activated B lymphocytes, make antibodies (immunoglobulins) that target specific antigens.

Why not B: Thrombocytes (platelets) help clotting.

Why not C: Erythrocytes (red cells) carry oxygen.

Why not D: Osteocytes are bone cells.

Exam tactic: B cells → antibodies.

Q4Which glands sit on top of the kidneys and release epinephrine?
  1. Parathyroid glands
  2. Thyroid glands
  3. Adrenal glands
  4. Pineal glands

Answer: C. The adrenal glands sit atop each kidney. The adrenal medulla releases epinephrine, and the adrenal cortex releases hormones such as cortisol and aldosterone.

Why not A: The parathyroids are on the thyroid.

Why not B: The thyroid is in the neck.

Why not D: The pineal gland is in the brain.

Exam tactic: Ad-renal = near the kidney.

Q5Which structure in the inner ear contains the hearing receptors?
  1. Auricle
  2. Cochlea
  3. Malleus
  4. Tympanic membrane

Answer: B. The snail-shaped cochlea in the inner ear converts sound vibrations into nerve impulses. The semicircular canals help with balance.

Why not A: The auricle is the external ear.

Why not C: The malleus is a middle-ear bone.

Why not D: The tympanic membrane (eardrum) is between the outer and middle ear.

Exam tactic: Cochlea = hearing.

Q6The shoulder and hip are examples of which type of joint?
  1. Ball-and-socket
  2. Saddle joints
  3. Hinge joints
  4. Pivot joints

Answer: A. Ball-and-socket joints allow movement in many directions, including rotation. The elbow and knee are hinge joints.

Why not B: Saddle joints, like the base of the thumb, move in two planes.

Why not C: Hinge joints move in one plane.

Why not D: Pivot joints allow rotation, like the neck.

Exam tactic: Shoulder/hip = ball-and-socket.

Q7Which pigment gives skin its color and helps protect against UV light?
  1. Hemoglobin
  2. Melanin
  3. Keratin
  4. Collagen

Answer: B. Melanin, produced by melanocytes in the epidermis, gives skin color and absorbs UV radiation.

Why not A: Hemoglobin carries oxygen in red blood cells.

Why not C: Keratin is a protective protein.

Why not D: Collagen gives strength to the dermis.

Exam tactic: Melanin = pigment.

Q8Which structure is commonly called the windpipe?
  1. Pharynx
  2. Trachea
  3. Larynx
  4. Esophagus

Answer: B. The trachea carries air from the larynx to the bronchi. It is held open by C-shaped cartilage rings.

Why not A: The pharynx is the throat.

Why not C: The larynx is the voice box.

Why not D: The esophagus carries food.

Exam tactic: Trachea = windpipe.

Q9What is the name of the wave-like muscle contractions that move food through the digestive tract?
  1. Peristalsis
  2. Defecation
  3. Mastication
  4. Emulsification

Answer: A. Peristalsis is the rhythmic contraction of smooth muscle that moves food along the digestive tract.

Why not B: Defecation is elimination of stool.

Why not C: Mastication is chewing.

Why not D: Emulsification breaks fats into droplets.

Exam tactic: Peristalsis = waves.

Q10Which part of a neuron receives signals from other cells?
  1. Myelin sheath
  2. Synaptic cleft
  3. Axon terminals
  4. Dendrites

Answer: D. Dendrites are branching extensions that receive incoming signals and carry them toward the cell body. The axon carries the impulse away from the cell body.

Why not A: Myelin insulates the axon to speed conduction.

Why not B: The synaptic cleft is the gap between neurons.

Why not C: Axon terminals release neurotransmitters to the next cell.

Exam tactic: Dendrites receive; axons send.

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More about the CCMA

PassPulse is an independent exam preparation tool. We are not affiliated with, endorsed by, or sponsored by the National Healthcareer Association (NHA), the American Association of Medical Assistants (AAMA), American Medical Technologists (AMT) or the National Center for Competency Testing (NCCT). Exam, credential and product names mentioned on this page are trademarks of their respective owners and are used only to identify the exams described.

These practice questions are written by PassPulse to reflect the published exam content outline. They are not actual exam questions. Questions, answers and explanations may contain errors or be out of date, and they are for exam study only, not for clinical or professional practice: always check facts against the certifying body's official materials, current standards and your employer's policies. Scores and projections on this page are estimates based on a small number of questions and do not predict your result on the real exam. Area weights come from the official outline as of the date shown; always confirm current exam details with the certifying body.
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